64,66,67 The regimen used in these trials was 1800 mg per day from day 3 of the menstrual cycle to oocyte aspiration (approximately 6 weeks)
They found that GLP-1 users had a 37% higher risk of alopecia than those taking SGLT-2 inhibitors, and a 68% higher risk compared with those using DPP-4 inhibitors
Among them, 8 (3.5%) patients were positive for cross-reactive ADA to nGIP, 1 (0.4%) patient was positive for cross-reactive ADA to nGLP-1, and 1 (0.4%) patient was positive for NAb against TZP activity on GIPR
Most common long-term side effects are gastrointestinal: nausea, vomiting, diarrhea, and constipation
magnesium proposed mechanism magnesium blocks the NMDA receptor channels in the spinal cord and thus limits the influx of calcium ie reduces the risk of excitotoxicity and consequent exacerbation of pain